We Only Deliver Magnitude Of Order Changes
We identify hyperfolding variants of a target protein with ten fold improved expression, solubility, and specific activity.Learn more
USPTO Awarded Aperiam Patent Claims Wherein Computer Vision Identifies Stabilizing Mutations.
Aperiam’s algorithms identify hyperfolding variants of a plastic degrading PETase enzyme at UT Austin, capable of breaking down common plastic goods in under 48 hours.
Aperiam’s algorithms identify a hyperfolding variant of a blue fluorescent protein BFP and increase fluorescence in bacteria over 10 fold with less than half a dozen mutations.
Nature’s toolset is far broader than we can use ourselves. We make manufacturing economics viable for our partners to produce otherwise inaccessible technical reagents.
Enzymes perform chemistry that is impossible with abiologic active ingredients, but most are not stable enough to work in consumer cosmetics. Our shelf-stable enzymes stay active for months and enable new cosmetic actives.
Natural human proteins mostly fall apart and can lose 90% of their activity if they are treated harshly in some applications, for example nebulization. We create therapeutics that, in our hands, retain over 68% activity in such application.